Nurse Practitioner Salary in St. Louis, MO-IL (2026)
Data updated · Sources: BLS OEWS May 2025, HUD FY 2027 Fair Market Rents, EPI 2026 Family Budget, 2026 tax tables · Methodology
Wage Benchmarking & After-Tax Paycheck Engine
Dynamic statutory tax calculations based on IRS Publication 15-T and state statutory schedules.
St. Louis, MO-IL Nurse Practitioner Wage Distribution
Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) Percentiles & Career Ladders
HUD Fair Market Rent & EPI Living Wage Affordability Index
Evaluating housing affordability vs. net take-home pay in St. Louis, MO-IL under the HUD 30% housing cost guideline.
Hourly Wage to Annual & Overtime Matrix
Translating base hourly pay and 1.5× overtime into net take-home pay based on 2,080 annual work hours in St. Louis, MO-IL.
Interstate MSA Relocation & State Tax Migration Comparator
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Combining state tax savings and annual rent variance when relocating from San Francisco-Oakland-Fremont, CA to Austin-Round Rock-San Marcos, TX.
Nurse Practitioner in St. Louis, MO-IL: Compensation & Purchasing Power Briefing (2026)
Estimates compiled from BLS OEWS wages, IRS 2026 withholding rules, HUD Fair Market Rents, and Missouri tax codes.
Key Economic & Compensation Takeaways
Statutory Withholding Architecture
Frequently Asked Questions
Wages sourced from US Bureau of Labor Statistics (BLS OEWS). Rents calibrated to HUD Fair Market Rents. Tax schedules calibrated to IRS IRC Title 26, IRS Pub 15-T, and state statutory revenue codes.
- Federal Standard Deduction (Single) $16,100
- FICA OASDI Wage Base Cap $184,500
- Pre-Tax 401(k) Elective Deferral $24,500
- HSA Individual Annual Limit $4,400
Nurse Practitioner in St. Louis, MO-IL: Market Snapshot
Nurse Practitioner roles in St. Louis, MO-IL report a median annual wage of $131,580, 0.5% below the national median of $132,300. The 10th to 90th percentile band runs from $108,340 to $164,280, and HUD’s $1,104 monthly one-bedroom fair market rent equals 10.1% of that median gross pay. The single-adult living wage benchmark for the area is $22.63 per hour.
Highest-paying metropolitan areas for Nurse Practitioner
| Metropolitan area | Median annual wage | Vs this market |
|---|---|---|
| San Jose-Sunnyvale-Santa Clara, CA | $231,560 | +76.0% |
| San Francisco-Oakland-Fremont, CA | $219,080 | +66.5% |
| Vallejo, CA | $182,370 | +38.6% |
| Napa, CA | $176,270 | +34.0% |
| Modesto, CA | $173,380 | +31.8% |
| Sacramento-Roseville-Folsom, CA | $172,010 | +30.7% |
| Riverside-San Bernardino-Ontario, CA | $169,920 | +29.1% |
| Hanford-Corcoran, CA | $168,540 | +28.1% |
| Santa Cruz-Watsonville, CA | $167,190 | +27.1% |
| Chico, CA | $167,080 | +27.0% |
Top-paying occupations benchmarked in St. Louis, MO-IL
| Occupation | Median annual wage | Median hourly |
|---|---|---|
| Chief Executives | $202,840 | $97.52/hr |
| Computer and Information Systems Managers | $167,130 | $80.35/hr |
| Architectural and Engineering Managers | $162,660 | $78.20/hr |
| Natural Sciences Managers | $158,820 | $76.36/hr |
| Financial Manager | $158,780 | $76.34/hr |
| Marketing Managers | $137,900 | $66.30/hr |
| Physician Assistant | $136,120 | $65.44/hr |
| Purchasing Managers | $135,400 | $65.10/hr |
| Human Resources Managers | $133,880 | $64.37/hr |
| Public Relations Managers | $130,280 | $62.63/hr |
Wage data: U.S. Bureau of Labor Statistics OEWS May 2025, 383 metropolitan areas publishing this occupation; HUD FY2027 Fair Market Rents; EPI Family Budget Calculator. Taxes use 2026 federal and state rules. Data last updated .
Regional Labor Market & Career Mobility Network
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Related Healthcare Roles in St. Louis, MO-IL
Roles in related occupations with transferable skills and overlapping employer demand.
Other Metros for Nurse Practitioner
Regional metropolitan labor markets within commuter or relocation distance with local BLS wages and living costs.
Nurse Practitioner median pay in St. Louis, MO-IL is $131,580 a year ($63.26/hr). See take-home pay after 2026 taxes, BLS wage percentiles, HUD rents & living.
Quick answers
The median annual wage is $131,580 ($63.26 per hour). The middle 80% of earners make between $108,340 and $164,280. Source: BLS OEWS (May 2025).
On the median wage of $131,580, a single filer with no pre-tax deductions takes home about $94,638 a year ($7,887 a month) after $36,942 in federal, FICA, state and local taxes, an effective rate of 28.08%, using 2026 tax rules.